Profhilo is an injection treatment that is performed just below the outer layer of the skin. In the epidermis, the hyaluronic acid spreads under controlled forms and regenerates with the skin’s tissues to immediately activate tProfhilo is an injection treatment that is performed just below the outer layer of the skin. In the epidermis, the hyaluronic acid spreads under controlled forms and regenerates with the skin’s tissues to immediately activate the natural hydration. As a result, the production of elastin and collagen increases, resulting in smoother, firmer and smoother skin. The most common areas to treat with PROFHILO are the face, neck and hands.he natural hydration. As a result, the production of elastin and collagen increases, resulting in smoother, firmer and smoother skin. The most common areas to treat with PROFHILO are the face, neck and hands.